Description

3',4'-Dibenzyloxyaceto-D3-Phenone is a high-purity, deuterated organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key labeled intermediate in the research and development of novel pharmaceutical compounds, where its isotopic label is crucial for metabolic and pharmacokinetic studies. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries working on deuterium-labeled active ingredients.

Application

• Pharmaceutical Intermediate: A critical labeled precursor in the synthesis of deuterated drug candidates for improved metabolic stability and bioavailability.
• Metabolic Tracer: Used in drug discovery and development as a stable isotope-labeled internal standard for mass spectrometry-based bioanalytical assays.
• Mechanistic Studies: Facilitates reaction pathway elucidation and kinetic isotope effect (KIE) studies in organic and medicinal chemistry research.
• Agrochemical Research: Serves as a building block for developing novel, labeled active ingredients with potential for enhanced environmental or biological profiles.
• Material Science: Potential intermediate for synthesizing specialized deuterated polymers or organic electronic materials where isotopic purity affects properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development of isotopically labeled compounds.

Basic Information

Product Name	3',4'-Dibenzyloxyaceto-D3-Phenone
CAS No.	344299-53-2
Molecular Formula	C22H17D3O3
Molecular Weight	335.42 g/mol
Synonyms	1-[3,4-Bis(benzyloxy)phenyl]ethanone-d3; 3',4'-Di-O-benzylaceto-D3-phenone; Deuterated 3,4-Dibenzyloxyacetophenone; Acetophenone-d3, 3',4'-bis(benzyloxy)-; 3,4-Dibenzyloxy-α,α,α-trideuteroacetophenone; (3,4-Dibenzyloxyphenyl)ethanone-d3; Labeled DBA-D3; 344299-53-2
EINECS	Contact for details

Quality Control

Our 3',4'-Dibenzyloxyaceto-D3-Phenone is manufactured under strict quality systems to ensure high isotopic and chemical purity, critical for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as chemical purity (HPLC), isotopic enrichment (NMR/MS), and identity confirmation. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.