Description

Phoscholin-D9 is a deuterated isotopologue of phosphatidylcholine, a critical phospholipid, where nine hydrogen atoms are replaced with deuterium. This stable isotope labeling is essential for advanced analytical research, providing a non-radioactive tracer with distinct mass spectral properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications such as metabolic pathway tracing, lipidomics, and as an internal standard for mass spectrometry.

Application

• Mass Spectrometry Internal Standard: Serves as a crucial quantitative reference standard in LC-MS and GC-MS analysis of phospholipids and their metabolites.
• Metabolic Research & Tracing: Used in deuterium labeling studies to investigate phospholipid biosynthesis, turnover, and metabolic pathways in biological systems.
• Lipidomics & Biomarker Discovery: Enables precise identification and quantification of phosphatidylcholine species in complex biological samples for disease research.
• Pharmaceutical R&D: Employed in drug development studies to understand drug-lipid interactions and the role of phospholipids in drug delivery systems.
• NMR Spectroscopy: Acts as a probe in nuclear magnetic resonance studies due to the distinct magnetic properties of deuterium.
• Stable Isotope Labeled Compound Production: Used as a building block or precursor for synthesizing more complex deuterated biochemicals.

Basic Information

Product Name	Phoscholin-D9
CAS No.	344299-43-0
Molecular Formula	C44H71D9NO8P
Molecular Weight	~ 809.1 g/mol (deuterated form)
Synonyms	1,2-Dipalmitoyl-d9-sn-glycero-3-phosphocholine; DPPC-d9; Deuterated Phosphatidylcholine; 1,2-Dihexadecanoyl-d9-sn-glycero-3-phosphocholine; Phosphatidylcholine-d9; 1,2-bis(hexadecanoyl-d9)-sn-glycero-3-phosphocholine; Deuterated DPPC; L-α-Phosphatidylcholine, dipalmitoyl, deuterated
EINECS	Contact for details

Quality Control

Every batch of Phoscholin-D9 is produced and analyzed under strict quality management protocols. We ensure high chemical purity and isotopic enrichment suitable for sensitive analytical applications. Comprehensive testing includes assay by NMR or HPLC, determination of deuterium enrichment, and analysis of related substances. A Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. For long-term storage, keep desiccated at -80°C.

Specification

Item	Specification
Appearance	White to off-white solid or waxy solid
Identification (NMR/HPLC)	Conforms to structure
Assay (by HPLC or 1H NMR)	≥ 95% (chemical purity)
Deuterium Enrichment	≥ 98 atom % D (per labeled position)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solubility	Soluble in chloroform, methanol; insoluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.