Description

1-Bromo-2-Methylpropane-3,3,3-D3 is a deuterated analog of isobutyl bromide, where three hydrogen atoms are replaced by deuterium, serving as a valuable labeled reagent for mechanistic studies and spectroscopic analysis. This compound is critical for researchers and manufacturers requiring precise isotopic labeling to track reaction pathways, enhance NMR signal resolution, or produce deuterated pharmaceuticals and advanced materials. It is primarily utilized in pharmaceutical R&D, agrochemical synthesis, and academic research focused on reaction kinetics and metabolic studies.

Application

• As a deuterated building block in the synthesis of isotopically labeled active pharmaceutical ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Use as a precursor or intermediate in the development of deuterated agrochemicals to study environmental fate and metabolic pathways.
• Employed in NMR spectroscopy as an internal standard or solvent for structural elucidation and quantitative analysis.
• Utilized in mechanistic organic chemistry research to investigate reaction mechanisms via kinetic isotope effect (KIE) studies.
• Application in material science for the synthesis of specialty polymers or liquid crystals with modified physical properties.
• Serving as a labeled starting material in the production of standards for mass spectrometry and other analytical techniques.

Basic Information

Product Name	1-Bromo-2-Methylpropane-3,3,3-D3
CAS No.	344299-42-9
Molecular Formula	C4H6D3Br
Molecular Weight	138.00 g/mol (approx.)
Synonyms	Isobutyl-d3 bromide; (2-Methylpropyl-d3) bromide; 1-Bromo-2-methyl-d3-propane; Deuterated isobutyl bromide; 2-Methyl-1-bromopropane-3,3,3-d3; tert-Butyl-d3 bromide (common misnomer); (CD3)2CDCH2Br
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Methylpropane-3,3,3-D3 is produced under controlled conditions to ensure high isotopic and chemical purity. Each batch undergoes rigorous quality testing, including assay by GC or NMR and deuterium enrichment analysis, to ensure compliance with customer specifications and research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic content, and physical properties is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flame. For long-term storage, consider keeping under an inert atmosphere to maintain purity.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Assay (GC)	≥ 98.0%
Deuterium Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.26 g/mL
Refractive Index (n20D)	~1.440

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.