Description

L-Lysine-3,3,4,4,5,5,6,6-D8 Hcl is a high-purity, deuterium-labeled derivative of the essential amino acid L-Lysine, specifically designed for use as an internal standard in quantitative mass spectrometry. This compound is critical for ensuring analytical accuracy and reproducibility in complex biological matrices. It is primarily utilized by research scientists and quality control laboratories in pharmaceutical development, clinical research, and metabolomics studies where precise quantification of L-Lysine is required.

Application

• Mass Spectrometry Internal Standard: Serves as a stable isotope-labeled internal standard for the accurate quantification of L-Lysine in LC-MS/MS and GC-MS applications.
• Pharmaceutical R&D: Used in pharmacokinetic (PK) and pharmacodynamic (PD) studies to track drug metabolism and amino acid uptake.
• Clinical Diagnostics & Metabolomics: Enables precise measurement of L-Lysine levels in plasma, serum, and tissue samples for disease biomarker research.
• Nutritional Science Research: Facilitates studies on protein metabolism, amino acid turnover, and nutritional status assessment.
• Biochemical Pathway Analysis: Aids in tracing metabolic fluxes and understanding the lysine biosynthesis and degradation pathways.
• Quality Control & Method Validation: Essential for developing and validating robust analytical methods in compliance with GLP and GMP guidelines.

Basic Information

Item	Details
Product Name	L-Lysine-3,3,4,4,5,5,6,6-D8 Hcl
CAS No.	344298-93-7
Molecular Formula	C6H7D8ClN2O2 • HCl
Molecular Weight	Approx. 231.20 g/mol
Synonyms	L-Lysine-d8 Hydrochloride; (2S)-2,6-Diamino-3,3,4,4,5,5,6,6-octadeuteriohexanoic Acid Hydrochloride; L-Lysine (3,3,4,4,5,5,6,6-D8) Hydrochloride; Deuterated L-Lysine HCl; L-Lysine-D8 HCl; Lysine-d8 HCl; (S)-2,6-Diaminocaproic Acid-d8 Hydrochloride
EINECS	Contact for details

Quality Control

Every batch of L-Lysine-3,3,4,4,5,5,6,6-D8 Hcl is manufactured and tested under strict quality management systems. We guarantee high chemical purity and isotopic enrichment, supported by comprehensive analytical data including NMR, Mass Spectrometry, and HPLC. Certificates of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and specific tests are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.