Description

n-Propyl-D7-Amine Hcl is a deuterium-labeled derivative of n-propylamine hydrochloride, a valuable isotopically labeled building block. This compound is specifically designed for use as an internal standard in quantitative mass spectrometry, ensuring high accuracy and reproducibility in analytical measurements. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and metabolomics fields who require precise tracking and quantification of propylamine-related compounds.

Application

• Mass Spectrometry Internal Standard: Primary use as a stable isotope-labeled internal standard for the accurate quantification of n-propylamine and its derivatives via LC-MS, GC-MS, or HRMS.
• Pharmaceutical Research & Metabolism Studies: Employed in drug metabolism and pharmacokinetics (DMPK) studies to trace the metabolic fate of drug candidates containing propylamine moieties.
• Analytical Method Development & Validation: Critical for developing and validating robust, regulatory-compliant analytical methods in GLP/GMP environments.
• Biochemical & Proteomics Research: Used in chemical proteomics and biochemical assays as a labeled reagent or tracer molecule.
• Environmental & Food Safety Testing: Applied in the detection and quantification of trace-level contaminants, pesticides, or residues where propylamine is a structural component.
• Synthetic Chemistry Intermediate: Serves as a labeled precursor for the synthesis of more complex deuterated molecules in medicinal and organic chemistry.

Basic Information

Product Name	n-Propyl-D7-Amine Hcl
CAS No.	344298-88-0
Molecular Formula	C3D7ClN
Molecular Weight	110.61 g/mol
Synonyms	1-Aminopropane-D7 hydrochloride; Propylamine-D7 hydrochloride; n-Propyl-D7-amine hydrochloride; Deuterated propylamine HCl; Perdeuteropropylamine hydrochloride; [2H7]Propylamine hydrochloride; 1-Propylamine-D7 HCl; Propanamine-D7 hydrochloride
EINECS	Contact for details

Quality Control

Every batch of n-Propyl-D7-Amine Hcl is produced and tested under strict quality management protocols to ensure exceptional isotopic purity and chemical integrity, critical for its role as an analytical standard. Our quality commitment includes comprehensive analysis by NMR, MS, and HPLC to verify isotopic enrichment (typically ≥98 atom % D) and chemical purity (≥95%). A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (NMR/MS)	≥ 98 atom % D
Chemical Purity (Titration)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.