Description

n-Butyl-D9-Amine Hcl is a high-purity, deuterium-labeled derivative of n-butylamine hydrochloride, a key building block in advanced chemical synthesis. This compound is specifically designed for applications requiring isotopic labeling, offering exceptional value in research and development where precise molecular tracking is essential. It is primarily utilized by pharmaceutical researchers, analytical chemists, and material scientists working in drug metabolism studies (DMPK), mass spectrometry, and the development of novel deuterated compounds.

Application

• Deuterated Internal Standards: Serves as a critical component in the synthesis of stable isotope-labeled internal standards for accurate quantification in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS).
• Pharmaceutical Research (DMPK): Used in Drug Metabolism and Pharmacokinetics (DMPK) studies to trace the metabolic pathways of drug candidates, enhancing the understanding of absorption, distribution, metabolism, and excretion (ADME).
• Synthetic Intermediate: Acts as a specialized building block for the preparation of more complex deuterated molecules, including active pharmaceutical ingredients (APIs) and advanced materials.
• NMR Spectroscopy: Employed in Nuclear Magnetic Resonance (NMR) spectroscopy as a deuterated reagent or precursor to simplify spectra and aid in structural elucidation.
• Metabolomics & Proteomics: Facilitates precise labeling in quantitative metabolomics and proteomics research, enabling high-fidelity comparative analysis.
• Chemical Biology Probes: Utilized in the development of chemical probes for investigating biological mechanisms and protein interactions with minimal background interference.

Basic Information

Product Name	n-Butyl-D9-Amine Hcl
CAS No.	344298-86-8
Molecular Formula	C4D9H3N·HCl
Molecular Weight	Contact for details
Synonyms	Butyl-d9-amine hydrochloride; Perdeuterated n-butylamine hydrochloride; 1-Aminobutane-d9 hydrochloride; n-Butylamine-d9 hydrochloride; Butan-1-amine-d9 hydrochloride; (Butyl-d9)amine hydrochloride; Deuterated n-butylamine HCl; 344298-86-8 (CAS)
EINECS	Contact for details

Quality Control

Our n-Butyl-D9-Amine Hcl is manufactured under strict quality systems to ensure batch-to-batch consistency and high isotopic purity. Each lot undergoes comprehensive analytical testing, including NMR, HPLC, and mass spectrometry, to confirm chemical and isotopic identity, purity, and absence of critical impurities. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-content)	≥98 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.