Description

3-Methylbutyric-D9 Acid is a stable isotope-labeled analog of isovaleric acid, where nine hydrogen atoms are replaced by deuterium. This high-purity compound is essential for applications requiring precise internal standards and metabolic pathway tracing in advanced analytical research. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors for quantitative mass spectrometry, NMR spectroscopy, and metabolic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Provides accurate quantification of isovaleric acid and related metabolites in complex biological matrices like plasma, urine, and tissue samples.
• Metabolic Pathway Tracing: Used in stable isotope labeling studies to investigate fatty acid metabolism, inborn errors of metabolism (e.g., isovaleric acidemia), and drug biotransformation pathways.
• NMR Spectroscopy: Serves as a deuterated solvent or reference compound in nuclear magnetic resonance studies due to its isotopic purity.
• Pharmaceutical Research & Development: Critical for pharmacokinetic (PK) and pharmacodynamic (PD) studies, enabling precise measurement of drug metabolites.
• Environmental and Food Safety Analysis: Acts as a labeled standard in the detection and quantification of volatile fatty acids in environmental samples and food products.
• Synthesis of Labeled Compounds: Used as a deuterated building block for the synthesis of more complex isotopically labeled molecules for research.

Basic Information

Product Name	3-Methylbutyric-D9 Acid
CAS No.	344298-81-3
Molecular Formula	C5D9HO2 or C5H1D9O2
Molecular Weight	113.19 g/mol (for C5D9HO2)
Synonyms	Isovaleric-d9 Acid; 3-Methylbutanoic-d9 Acid; Isopentanoic-d9 Acid; (CH3)2CHCH2COOD (deuterated form); Deuterated Isovaleric Acid; D9-Isovaleric Acid; Perdeuterated 3-Methylbutyric Acid; 344298-81-3
EINECS	Contact for details

Quality Control

Our 3-Methylbutyric-D9 Acid is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including NMR and GC/MS, to confirm isotopic purity (typically ≥98 atom % D) and chemical purity. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR/NMR)	Conforms to structure
Isotopic Purity (Atom % D)	≥98% (by NMR)
Chemical Purity (GC)	≥98%
Water Content (KF)	≤0.5%
Specific Rotation	Contact for details
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.