Description

2-Propanone, 1-(2-Fluorocyclobutylidene)- (9Ci) is a specialized fluorinated ketone building block with the CAS number 344247-26-3. This compound is valued for its unique structural motif, which combines a reactive α,β-unsaturated ketone system with a fluorinated cyclobutylidene moiety, making it a versatile intermediate in advanced synthetic chemistry. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel, fluorinated active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in medicinal chemistry programs, particularly for introducing fluorinated cyclobutane rings to modulate bioavailability and metabolic stability.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and environmental persistence.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored thermal and chemical resistance properties.
• Organic Synthesis Building Block: Employed in cycloaddition reactions, Michael additions, and other transformations to create complex, fluorinated organic frameworks in academic and industrial R&D.
• Fluorine Chemistry Studies: Utilized as a model compound for investigating the reactivity and stereoelectronic effects of fluorinated alkenes and ketones.

Basic Information

Product Name	2-Propanone, 1-(2-Fluorocyclobutylidene)- (9Ci)
CAS No.	344247-26-3
Molecular Formula	C7H9FO
Molecular Weight	128.15 g/mol
Synonyms	1-(2-Fluorocyclobutylidene)propan-2-one; 2-Fluoro-1-(1-methylvinylidene)cyclobutane; 2-Propanone, 1-(2-fluorocyclobutylidene)-; (2-Fluorocyclobutylidene)acetone; Fluorocyclobutylidene acetone; 344247-26-3
EINECS	Contact for details

Quality Control

Our 2-Propanone, 1-(2-Fluorocyclobutylidene)- (9Ci) is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for reliable sourcing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases, reducing agents, and sources of ignition. For long-term storage, consider maintaining under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.