Description

3-(Cyanoacetyl)-1-Methylindole is a versatile indole derivative characterized by a reactive cyanoacetyl functional group. This compound serves as a crucial synthetic intermediate for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors. Its unique structure enables key transformations in organic synthesis, making it valuable for developing novel compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of indole-based drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: Employed in cyclization and condensation reactions to create complex heterocyclic compounds for material science.
• Dye and Pigment Precursor: Serves as an intermediate in the production of specialized dyes and organic pigments.
• Biochemical Research: Utilized in academic and industrial R&D for studying enzyme inhibitors and receptor ligands.
• Material Science: A precursor for advanced organic electronic materials and functional polymers.

Basic Information

Product Name	3-(Cyanoacetyl)-1-Methylindole
CAS No.	343778-74-5
Molecular Formula	C₁₂H₁₀N₂O
Molecular Weight	198.22 g/mol
Synonyms	1-Methyl-3-(cyanoacetyl)indole; 3-(2-Cyanoacetyl)-1-methyl-1H-indole; 1H-Indole-3-acetonitrile, 1-methyl-, α-oxo-; 3-(Cyanoacetyl)-1-methylindole; 1-Methylindole-3-glyoxylonitrile; (1-Methyl-1H-indol-3-yl)-2-oxoacetonitrile; 2-Oxo-2-(1-methyl-1H-indol-3-yl)acetonitrile
EINECS	Contact for details

Quality Control

Our 3-(Cyanoacetyl)-1-Methylindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.