Description

1,3,5-Triazabicyclo[3.2.2]Nonane(9Ci) is a bicyclic guanidine derivative known for its strong, non-nucleophilic base properties. This compound is highly valued for its role in facilitating challenging organic transformations, particularly in the synthesis of complex molecules where minimal nucleophilic interference is critical. It is an essential reagent for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, enabling efficient deprotonation and catalysis under mild conditions.

Application

• Pharmaceutical Synthesis: Acts as a powerful, non-nucleophilic base in the production of active pharmaceutical ingredients (APIs), especially for sensitive reactions involving esters, amides, and carbon acids.
• Polymer Chemistry: Utilized as an efficient catalyst or initiator in the polymerization of lactones, carbonates, and other monomers to create specialized polyesters and polycarbonates.
• Agrochemical Manufacturing: Employed in the synthesis of advanced herbicides, fungicides, and insecticides where selective base catalysis is required.
• Organic Synthesis Reagent: Facilitates a wide range of reactions including Henry reactions, Michael additions, and isomerizations under mild conditions.
• Chemical Research & Development: Serves as a key reagent in methodological development and scale-up studies for novel synthetic pathways in academic and industrial labs.
• Fine Chemical Production: Used in the manufacture of dyes, flavors, fragrances, and other high-value specialty chemicals requiring precise base-mediated steps.

Basic Information

Item	Details
Product Name	1,3,5-Triazabicyclo[3.2.2]Nonane(9Ci)
CAS No.	343264-98-2
Molecular Formula	C6H11N3
Molecular Weight	125.17 g/mol
Synonyms	1,3,5-Triazabicyclo[3.2.2]nonane; TBN; Bicyclic Guanidine Base; 1,5,7-Triazabicyclo[3.2.2]nonane; 7-Azabicyclo[3.2.2]nonane-1,5-diamine; 1,3,5-Triazabicyclo[3.2.2]nonane (TBN); Strong Organic Base TBN; 343264-98-2
EINECS	Contact for details

Quality Control

Our 1,3,5-Triazabicyclo[3.2.2]Nonane(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting full specifications are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.