Description

2-Phenylethyl-D9-Amine is a deuterium-labeled analog of phenethylamine, where nine hydrogen atoms are replaced with the stable isotope deuterium. This high isotopic purity makes it an essential internal standard and reference material for precise quantitative analysis in mass spectrometry-based applications. It is primarily used by researchers and quality control laboratories in the pharmaceutical, forensic, and metabolomics fields to ensure accurate and reliable measurement of its non-labeled counterpart and related compounds.

Application

• Internal Standard for LC-MS/MS: Critical for the accurate quantification of phenethylamine and its derivatives in complex biological matrices like plasma, urine, and tissue samples.
• Pharmaceutical Research & Development: Used in drug metabolism and pharmacokinetic (DMPK) studies to track the absorption, distribution, metabolism, and excretion of candidate drugs.
• Forensic Toxicology: Serves as a reference standard for the confirmatory analysis of amphetamine-type substances, enhancing the reliability of analytical results.
• Metabolomics and Biomarker Discovery: Enables precise measurement of endogenous phenethylamine levels in studies investigating neurological and metabolic disorders.
• Chemical Synthesis: Acts as a labeled building block for the synthesis of more complex deuterated compounds for research purposes.
• Quality Control (QC) in Manufacturing: Employed in QC laboratories to validate analytical methods and ensure the accuracy of purity assays for related active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2-Phenylethyl-D9-Amine
CAS No.	342661-05-6
Molecular Formula	C8D9N
Molecular Weight	~131.23 g/mol
Synonyms	Phenethylamine-D9; 2-Phenylethylamine-D9; β-Phenylethylamine-D9; (2-Aminoethyl)benzene-D9; Benzeneethanamine-D9; 1-Amino-2-phenylethane-D9; PEA-D9; Deutero-Phenethylamine (D9)
EINECS	Contact for details

Quality Control

Our 2-Phenylethyl-D9-Amine is manufactured under strict quality control protocols to ensure high chemical and isotopic purity suitable for analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry, to confirm identity, chemical purity, and deuterium incorporation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be stored away from light to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 99.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.