Description

2-Phenylethyl-D9-Amine is a deuterium-labeled analog of phenethylamine, where nine hydrogen atoms are replaced with the stable isotope deuterium. This high isotopic purity makes it an essential internal standard and tracer in quantitative mass spectrometry, ensuring analytical accuracy and reliability. It is primarily used by research institutions, pharmaceutical developers, and analytical laboratories engaged in pharmacokinetic studies, metabolic pathway analysis, and the development of deuterated drug candidates.

Application

• Internal Standard for LC-MS/MS: Critical for the accurate quantification of phenethylamine and its derivatives in complex biological matrices like plasma, urine, and tissue samples.
• Metabolic Research: Used as a stable isotope tracer to study the absorption, distribution, metabolism, and excretion (ADME) profiles of bioactive amines.
• Pharmaceutical Development: Serves as a key starting material or reference compound in the synthesis and analysis of deuterated pharmaceuticals, where deuterium incorporation can alter metabolic stability.
• Forensic and Clinical Toxicology: Employed in confirmatory testing and method development for the detection of amphetamine-type substances and related compounds.
• Biochemical Pathway Analysis: Facilitates research into neurotransmitter systems and the role of trace amines in neurological function and disorders.
• Quality Control in Reference Material Production: Used to certify and validate the purity and concentration of unlabeled phenethylamine standards.

Basic Information

Product Name	2-Phenylethyl-D9-Amine
CAS No.	342611-05-6
Molecular Formula	C8D9N
Molecular Weight	~131.23 g/mol
Synonyms	Phenethylamine-D9; β-Phenylethylamine-D9; 2-Phenylethan-1-amine-D9; (2-Aminoethyl)benzene-D9; Benzeneethanamine-D9; PEA-D9; Deutero-Phenethylamine; d9-Phenethylamine
EINECS	Contact for details

Quality Control

Every batch of 2-Phenylethyl-D9-Amine is produced and analyzed under strict quality management protocols to ensure exceptional isotopic and chemical purity. Our products undergo rigorous quality testing, including NMR, HPLC, and mass spectrometry, to ensure compliance with research and analytical standards. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (e.g., D9 > 98%), chemical purity, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	D9 ≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.