Description

5-(4-Methylphenyl)-4-(1-Pyrrolidinyl)Thieno[2,3-D]Pyrimidine is a high-purity, advanced pharmaceutical intermediate belonging to the thienopyrimidine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the research and development of novel therapeutic agents, particularly in oncology and other disease areas. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of kinase inhibitors and other targeted small-molecule drugs.
• Oncology Research: Used in the discovery and optimization of novel anti-cancer compounds due to the thienopyrimidine scaffold's biological relevance.
• Chemical Biology: Employed as a molecular probe or tool compound for studying specific biological pathways and target validation.
• Medicinal Chemistry: Provides a versatile core structure for structure-activity relationship (SAR) studies and lead optimization programs.
• Custom Synthesis: Supplied to fine chemical companies for use in multi-step synthesis projects under cGMP or research-grade conditions.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	5-(4-Methylphenyl)-4-(1-Pyrrolidinyl)Thieno[2,3-D]Pyrimidine
CAS No.	342595-74-8
Molecular Formula	C17H17N3S
Molecular Weight	295.40 g/mol
Synonyms	4-(1-Pyrrolidinyl)-5-(p-tolyl)thieno[2,3-d]pyrimidine; 5-(4-Methylphenyl)-4-(pyrrolidin-1-yl)thieno[2,3-d]pyrimidine; Thieno[2,3-d]pyrimidine, 5-(4-methylphenyl)-4-(1-pyrrolidinyl)-; 342595-74-8; 5-(p-Tolyl)-4-(pyrrolidin-1-yl)thieno[2,3-d]pyrimidine; 4-Pyrrolidin-1-yl-5-(4-methylphenyl)thieno[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 5-(4-Methylphenyl)-4-(1-Pyrrolidinyl)Thieno[2,3-D]Pyrimidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, related substances, and residual solvents. Our quality commitment supports research and development requiring reliable and traceable materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect the product from moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.