Description

1H-Indole-3-Carbonylchloride,2-Methyl-(9Ci) is a specialized indole derivative, specifically an acid chloride, that serves as a crucial building block in advanced organic synthesis. Its reactive carbonyl chloride group makes it an essential intermediate for constructing complex molecules, particularly in the development of pharmaceuticals and agrochemicals. This high-purity intermediate is primarily sought by research institutions and industrial manufacturers engaged in the synthesis of novel active compounds, where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting neurological and oncological pathways.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators that leverage the indole scaffold.
• Material Science: Building block for creating specialized polymers and organic electronic materials with unique optoelectronic properties.
• Bioconjugation Chemistry: Employed to attach indole-based probes or labels to biomolecules for diagnostic and research applications.
• Academic & Contract Research: Essential reagent for medicinal chemistry programs and library synthesis in drug discovery.
• Fine Chemical Synthesis: Intermediate for producing other complex indole derivatives, dyes, and pigments.

Basic Information

Product Name	1H-Indole-3-Carbonylchloride,2-Methyl-(9Ci)
CAS No.	342411-94-3
Molecular Formula	C10H8ClNO
Molecular Weight	193.63 g/mol
Synonyms	2-Methyl-1H-indole-3-carbonyl chloride; 2-Methylindole-3-carbonyl chloride; 2-Methyl-1H-indole-3-carboxylic acid chloride; 2-Methylindole-3-carboxylic acid chloride; 1H-Indole-3-carbonylchloride, 2-methyl- (9CI); 2-Methyl-1H-indole-3-carbonylchloride; 342411-94-3
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Carbonylchloride,2-Methyl-(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.