Description

1-(Iodomethyl)-Pyrrolidine is a versatile organoiodine building block featuring a reactive iodomethyl group attached to a pyrrolidine ring. This compound is highly valued in synthetic organic chemistry for its role as an efficient alkylating agent and intermediate in the construction of complex nitrogen-containing molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrrolidine or substituted amine moieties.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization for introducing functional groups via alkylation reactions.
• Agrochemical Synthesis: Intermediate in the production of herbicides, fungicides, and other crop protection agents that require specific nitrogen heterocycles.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and cross-coupling reactions.
• Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and constructing complex molecular architectures.
• Material Science: Potential monomer or functionalization agent in the development of advanced polymers and functional materials.

Basic Information

Item	Details
Product Name	1-(Iodomethyl)-Pyrrolidine
CAS No.	342401-48-3
Molecular Formula	C5H10IN
Molecular Weight	211.05 g/mol
Synonyms	N-(Iodomethyl)pyrrolidine; Pyrrolidine, 1-(iodomethyl)-; 1-Iodomethylpyrrolidine; N-Iodomethylpyrrolidine; (Iodomethyl)pyrrolidine; 342401-48-3; Iodomethylpyrrolidine
EINECS	Contact for details

Quality Control

Our 1-(Iodomethyl)-Pyrrolidine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant packaging.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.