Description

2-(3,4,5-Trimethoxyphenyl)-6,7-Dihydro-4H,5H-Cyclopenta[4,5]Thieno[2,3-D][1,3]Oxazin-4-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex fused-ring systems containing thieno[2,3-d][1,3]oxazine motifs.
• Process Development & Scale-Up: Supplied in development and commercial quantities to support route scouting, optimization, and cGMP manufacturing campaigns.

Basic Information

Product Name	2-(3,4,5-Trimethoxyphenyl)-6,7-Dihydro-4H,5H-Cyclopenta[4,5]Thieno[2,3-D][1,3]Oxazin-4-One
CAS No.	342381-89-9
Molecular Formula	C19H19NO5S
Molecular Weight	373.42 g/mol
Synonyms	Cyclopenta[4,5]thieno[2,3-d][1,3]oxazin-4-one, 2-(3,4,5-trimethoxyphenyl)-6,7-dihydro-5H-; 5H-Cyclopenta[4,5]thieno[2,3-d][1,3]oxazin-4-one, 2-(3,4,5-trimethoxyphenyl)-6,7-dihydro-; CAS 342381-89-9; 2-(3,4,5-Trimethoxyphenyl)-5H-cyclopenta[4,5]thieno[2,3-d][1,3]oxazin-4(6H,7H)-one
EINECS	Contact for details

Quality Control

Our 2-(3,4,5-Trimethoxyphenyl)-6,7-Dihydro-4H,5H-Cyclopenta[4,5]Thieno[2,3-D][1,3]Oxazin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.