Description

Tryptamine-Alpha,Alpha,Beta,β-D4 Hcl CAS NO 340257-60-5 is a deuterium-labeled analog of tryptamine hydrochloride, a key biochemical building block. This stable isotope-labeled compound is essential for advanced research requiring precise metabolic and pharmacokinetic tracing. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on neuroscience, drug metabolism, and analytical method development.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative reference standard in bioanalytical assays for neurotransmitter and tryptamine metabolite analysis.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used as a tracer to study the absorption, distribution, metabolism, and excretion (ADME) of tryptamine-related compounds.
• Neuroscience Research: Employed in investigations of serotonin biosynthesis pathways, trace amine-associated receptors (TAARs), and related neurological mechanisms.
• Isotope Dilution Mass Spectrometry (IDMS): Provides high-accuracy quantification in complex biological matrices for clinical and forensic toxicology.
• Synthetic Intermediate: Acts as a labeled precursor for the synthesis of more complex deuterated molecules for research and development.

Basic Information

Product Name	Tryptamine-Alpha,Alpha,Beta,β-D4 Hcl
CAS No.	340257-60-5
Molecular Formula	C₁₀H₁₁D₄N₂•HCl
Molecular Weight	202.73 g/mol
Synonyms	2-(1H-Indol-3-yl)ethan-1,1,2,2-d4-amine hydrochloride; Tryptamine-α,α,β,β-d4 hydrochloride; Deuterated Tryptamine HCl; [α,α,β,β-2H4]Tryptamine hydrochloride; 3-(2-Aminoethyl-d4)indole hydrochloride; Tryptamine-d4 HCl; TA-d4 HCl; 2-(3-Indolyl)ethyl-1,1,2,2-d4-amine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of our deuterated tryptamine HCl is produced and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR, HPLC, and mass spectrometry to confirm identity, potency, and deuterium incorporation. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert conditions after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.