Description

1-(3-Bromo-2-Thienyl)-3-(2,4-Dichlorophenyl)-2-Propen-1-One is a high-purity, synthetic organic compound featuring a chalcone core structure with bromothiophene and dichlorophenyl substituents. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis due to its reactive α,β-unsaturated ketone moiety.
• Agrochemical Development: Used in the research and development of new pesticides and herbicides, leveraging its halogenated aromatic systems.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the development of specialized polymers and organic electronic materials.
• Chemical Biology Probe: Employed in biochemical assays to study protein-ligand interactions and enzyme inhibition.

Basic Information

Product Name	1-(3-Bromo-2-Thienyl)-3-(2,4-Dichlorophenyl)-2-Propen-1-One
CAS No.	339113-88-1
Molecular Formula	C13H7BrCl2OS
Molecular Weight	362.07 g/mol
Synonyms	(E)-1-(3-Bromothiophen-2-yl)-3-(2,4-dichlorophenyl)prop-2-en-1-one; 3-Bromo-2-thienyl 2,4-dichlorophenyl ketone, chalcone derivative; 1-(3-Bromo-2-thienyl)-3-(2,4-dichlorophenyl)-2-propen-1-one; 3'-Bromo-2,4-dichlorochalcone; (E)-3-(2,4-Dichlorophenyl)-1-(3-bromothiophen-2-yl)prop-2-en-1-one; 2-Propen-1-one, 1-(3-bromo-2-thienyl)-3-(2,4-dichlorophenyl)-; Bromodichlorophenyl thienyl propenone
EINECS	Contact for details

Quality Control

Our 1-(3-Bromo-2-Thienyl)-3-(2,4-Dichlorophenyl)-2-Propen-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.