Description

Methyl 3-[(3-Chloro-2,2-Dimethylpropanoyl)Amino]-2-Thiophenecarboxylate is a high-purity, specialized organic intermediate featuring a thiophene core with a chloro-dimethylpropanoyl amide substituent. This compound matters for its role as a critical building block in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the agrochemical and pharmaceutical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders or infectious diseases.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced pesticides and herbicides, leveraging the thiophene moiety for biological activity.
• Material Science Research: Used in the development of novel organic semiconductors or conductive polymers due to its conjugated thiophene structure.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms or protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital component for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	Methyl 3-[(3-Chloro-2,2-Dimethylpropanoyl)Amino]-2-Thiophenecarboxylate
CAS No.	339100-27-5
Molecular Formula	C11H14ClNO3S
Molecular Weight	275.75 g/mol
Synonyms	Methyl 3-[(3-chloro-2,2-dimethylpropanoyl)amino]thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-[(3-chloro-2,2-dimethyl-1-oxopropyl)amino]-, methyl ester; 3-[(3-Chloro-2,2-dimethylpropanoyl)amino]-2-thiophenecarboxylic acid methyl ester; Methyl 3-(3-chloro-2,2-dimethylpropanamido)thiophene-2-carboxylate; CAS 339100-27-5
EINECS	Contact for details

Quality Control

Our Methyl 3-[(3-Chloro-2,2-Dimethylpropanoyl)Amino]-2-Thiophenecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.