Description

2-(1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1H-Indol-3-Yl)Acetic Acid is a high-value, non-natural amino acid derivative and a sophisticated heterocyclic building block. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its unique molecular scaffold enables the introduction of specific biological activity. It is primarily required by research and development teams in the pharmaceutical and agrochemical industries for lead optimization and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, leveraging the pyridine and indole motifs for targeted biological action.
• Chemical Research: Serves as a versatile building block in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Process Development: Employed in scale-up and route scouting for the commercial manufacturing of complex active ingredients.
• Bioconjugation: The acetic acid functional group allows for potential use in linker chemistry for antibody-drug conjugates (ADCs) or prodrug strategies.

Basic Information

Product Name	2-(1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1H-Indol-3-Yl)Acetic Acid
CAS No.	339099-14-8
Molecular Formula	C₁₆H₁₀ClF₃N₂O₂
Molecular Weight	354.71 g/mol
Synonyms	2-[1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]indol-3-yl]acetic acid; 2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)acetic acid; 339099-14-8; 2-(1-(3-Chloro-5-(trifluoromethyl)-2-pyridinyl)-1H-indol-3-yl)acetic acid; 2-(1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-indol-3-yl)ethanoic acid
EINECS	Contact for details

Quality Control

Our production of 2-(1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-1H-Indol-3-Yl)Acetic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical and agrochemical R&D. Certificates of Analysis (COA) with full traceability are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled under inert conditions for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.