Description

Piperidine-D10 Hcl CAS NO 339080-76-1 is a deuterium-labeled analog of piperidine hydrochloride, where ten hydrogen atoms are replaced by deuterium, serving as a critical internal standard and tracer in analytical chemistry. This high isotopic purity compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry and NMR spectroscopy analyses. It is primarily utilized by pharmaceutical research laboratories, contract research organizations (CROs), and academic institutions engaged in drug metabolism and pharmacokinetics (DMPK) studies.

Application

• Internal Standard for LC-MS/MS: Used as a stable, non-interfering reference compound for the precise quantification of piperidine and related alkaloids or pharmaceutical intermediates in complex biological matrices.
• Metabolic Pathway Tracing: Employed in drug discovery and development to track and elucidate metabolic pathways and biotransformation products of candidate drugs.
• NMR Spectroscopy Solvent & Reagent: Acts as a deuterated reagent or shift reference in nuclear magnetic resonance (NMR) experiments to avoid signal interference from protons.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradation products in active pharmaceutical ingredients (APIs).
• Forensic and Toxicological Analysis: Supports accurate detection and measurement of piperidine-based compounds in forensic science and clinical toxicology.
• Chemical Synthesis Research: Serves as a labeled building block in the synthesis of deuterated complex molecules for various research applications.

Basic Information

Product Name	Piperidine-D10 Hcl
CAS No.	339080-76-1
Molecular Formula	C5D10N·HCl
Molecular Weight	127.68 g/mol
Synonyms	Perdeuterated Piperidine Hydrochloride; Piperidine-d10 Hydrochloride; Deuterated Piperidine HCl; Hexadeuteriopyridine-d10 Hydrochloride; 1-Azacyclohexane-d10 Hydrochloride; Azacyclohexane-d10 Hydrochloride; Pentamethyleneimine-d10 Hydrochloride; Cyclopentimine-d10 Hydrochloride
EINECS	Contact for details

Quality Control

Our Piperidine-D10 Hcl is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity, meeting the stringent requirements of analytical and research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic purity (Atom % D), chemical purity (by HPLC/NMR), and residual solvent content. We adhere to rigorous quality testing protocols to guarantee batch-to-batch consistency and reliability for your critical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Atom % D)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.