Description

Glyceryl Trihexadecanoate-13C2 [1,3-Di(Hexadecanoate-1-13C)] is a stable isotope-labeled analog of tripalmitin, where two of the palmitate chains are specifically enriched with carbon-13 at the C-1 position. This compound is essential for providing an internal standard with minimal isotopic interference, ensuring unparalleled accuracy and precision in quantitative mass spectrometry and metabolic flux analysis. It is primarily required by researchers and analytical laboratories in the pharmaceutical, nutritional science, and lipid metabolism sectors for method development, validation, and high-fidelity tracer studies.

Application

• Internal Standard for Quantitative LC-MS/MS Analysis: Used for the precise quantification of triglycerides and their metabolites in complex biological matrices like plasma, serum, and tissue homogenates.
• Metabolic Tracer Studies: Enables detailed investigation of lipid biosynthesis, β-oxidation pathways, and energy metabolism in cell cultures and animal models.
• Stable Isotope Dilution Mass Spectrometry (SID-MS): Serves as a critical reference compound to correct for analyte loss during sample preparation and instrument variability.
• Pharmaceutical R&D: Supports drug discovery and development programs focused on metabolic diseases, obesity, and diabetes by providing reliable data on lipid turnover.
• Nutritional Research: Facilitates studies on fat absorption, digestion, and the metabolic fate of dietary lipids in human and animal subjects.
• Quality Control in Analytical Laboratories: Employed to validate analytical methods, ensure compliance with GLP/GMP guidelines, and maintain the integrity of long-term studies.

Basic Information

Product Name	Glyceryl Trihexadecanoate-13C2 [1,3-Di(Hexadecanoate-1-13C)]
CAS No.	339080-65-8
Molecular Formula	C51H9813C2O6
Molecular Weight	~ 821.34 g/mol (for unlabeled C51H98O6)
Synonyms	1,3-Di(Hexadecanoate-1-13C) Glycerol; Tripalmitin-13C2; [1,3-13C2]Tripalmitin; Glyceryl Tripalmitate-13C2; 1,2,3-Trihexadecanoyl-13C2-glycerol; Palmitic-1-13C Acid Triglyceride (1,3-labeled); Glycerol Trihexadecanoate-13C2; (13C2)Glycerol Tripalmitate
EINECS	Contact for details

Quality Control

Every batch of our isotope-labeled compounds is produced and verified under a strict quality management system. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR and mass spectrometry for structural confirmation and isotopic enrichment verification. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting the exact specifications, batch number, and analytical results to ensure traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (MS)	≥ 99 atom % 13C at specified positions
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.