Description

Benzo[B]Thiophen-7(4H)-One, 6-Fluoro-5,6-Dihydro- is a high-value fluorinated heterocyclic building block, specifically a dihydrobenzothiophenone derivative, essential for advanced synthetic chemistry. Its core value lies in its unique molecular scaffold, which serves as a critical intermediate for constructing complex molecules in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and infectious diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science Precursor: Serves as a building block for organic electronic materials, such as novel semiconductors or charge-transport materials, due to its fused thiophene core.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic & Institutional Research: Utilized in university and government laboratories for fundamental research in synthetic organic chemistry and medicinal chemistry.

Basic Information

Product Name	Benzo[B]Thiophen-7(4H)-One, 6-Fluoro-5,6-Dihydro-
CAS No.	339056-43-8
Molecular Formula	C8H5FOS
Molecular Weight	168.19 g/mol
Synonyms	6-Fluoro-4,5-dihydro-1-benzothiophen-7(6H)-one; 6-Fluoro-5,6-dihydrobenzo[b]thiophen-7(4H)-one; 6-Fluoro-4,5,6,7-tetrahydro-1-benzothiophen-7-one; 7H-Benzo[b]thiophen-7-one, 6-fluoro-4,5-dihydro-; 6-Fluoro-4,5-dihydrobenzo[b]thiophen-7(6H)-one; Fluorinated dihydrobenzothiophenone; 6-Fluoro-5,6-dihydro-7H-1-benzothiophen-7-one
EINECS	Contact for details

Quality Control

Our Benzo[B]Thiophen-7(4H)-One, 6-Fluoro-5,6-Dihydro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment. We support compliance with relevant frameworks for advanced intermediates, and specifications can be aligned with client-specific pharmacopeial or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider inert atmosphere packaging to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.