Description

4-Chloro-6-[3,4-Dihydro-2(1H)-Isoquinolinyl]-2-Pyrimidinamine is a high-purity, heterocyclic organic compound featuring a fused pyrimidine-isoquinoline core structure. This specialized chemical building block is valued for its role as a key intermediate in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its fused heterocyclic scaffold.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, or insecticides with novel modes of action.
• Chemical Biology Probe: Used in medicinal chemistry to explore structure-activity relationships (SAR) and identify new biological targets.
• Organic Synthesis Reagent: Employed in academic and industrial laboratories for constructing complex nitrogen-containing heterocycles.
• Material Science Research: Potential intermediate for creating organic electronic materials or ligands for catalytic systems.

Basic Information

Product Name	4-Chloro-6-[3,4-Dihydro-2(1H)-Isoquinolinyl]-2-Pyrimidinamine
CAS No.	339015-95-1
Molecular Formula	C13H13ClN4
Molecular Weight	260.72 g/mol
Synonyms	4-Chloro-6-(1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidin-2-amine; 2-Pyrimidinamine, 4-chloro-6-(3,4-dihydro-2(1H)-isoquinolinyl)-; 4-Chloro-6-(1,2,3,4-tetrahydro-2-isoquinolinyl)-2-pyrimidinamine; 4-Chloro-6-(3,4-dihydro-1H-isoquinolin-2-yl)pyrimidin-2-amine; CAS 339015-95-1
EINECS	Contact for details

Quality Control

Our 4-Chloro-6-[3,4-Dihydro-2(1H)-Isoquinolinyl]-2-Pyrimidinamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.