Description

1-(Cyanomethyl)-N-[4-(Trifluoromethyl)Phenyl]-3,4-Dihydro-2(1H)-Isoquinolinecarboxamide is a high-purity, advanced pharmaceutical intermediate designed for precision synthesis. This compound matters for its role as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and metabolic disorders. Pharmaceutical R&D teams and fine chemical manufacturers need this material to enable efficient, scalable routes to complex drug candidates, ensuring process reliability and regulatory compliance.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel therapeutic agents, particularly for neurological and psychiatric applications.
• Chemical Biology Research: Used as a molecular scaffold or probe in drug discovery and target validation studies.
• Process Chemistry Development: Serves as a critical building block for optimizing synthetic routes and scaling up API production under GMP conditions.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents with specific biological activity.
• Material Science: Potential use in the synthesis of specialty polymers or organic electronic materials due to its fused ring and functional group architecture.

Basic Information

Product Name	1-(Cyanomethyl)-N-[4-(Trifluoromethyl)Phenyl]-3,4-Dihydro-2(1H)-Isoquinolinecarboxamide
CAS No.	339011-97-1
Molecular Formula	C19H16F3N3O
Molecular Weight	359.35 g/mol
Synonyms	1-(Cyanomethyl)-N-[4-(trifluoromethyl)phenyl]-3,4-dihydroisoquinoline-2(1H)-carboxamide; 1-(Cyanomethyl)-N-[4-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydroisoquinoline-2-carboxamide; 339011-97-1; N-(4-(Trifluoromethyl)phenyl)-1-(cyanomethyl)-3,4-dihydro-2(1H)-isoquinolinecarboxamide; 1-(Cyanomethyl)-N-(4-trifluoromethylphenyl)-1,2,3,4-tetrahydroisoquinoline-2-carboxamide
EINECS	Contact for details

Quality Control

Our production of 1-(Cyanomethyl)-N-[4-(Trifluoromethyl)Phenyl]-3,4-Dihydro-2(1H)-Isoquinolinecarboxamide adheres to stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure compliance with client specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.