Description

1-(Cyanomethyl)-n-[3-(Trifluoromethyl)Phenyl]-3,4-Dihydro-2(1H)-Isoquinolinecarboxamide is a high-value, specialized organic intermediate featuring a unique isoquinoline core functionalized with a cyanomethyl group and a trifluoromethylphenyl carboxamide moiety. This compound matters for its role as a critical building block in modern pharmaceutical and agrochemical research, enabling the synthesis of novel molecules with targeted biological activity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Chemical Biology Probe: Acts as a scaffold for creating tool compounds to study enzyme function and biological pathways.
• Material Science: Potential building block for advanced organic electronic materials or liquid crystals due to its rigid, aromatic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and fluoroorganic chemistry.

Basic Information

Product Name	1-(Cyanomethyl)-n-[3-(Trifluoromethyl)Phenyl]-3,4-Dihydro-2(1H)-Isoquinolinecarboxamide
CAS No.	339011-95-9
Molecular Formula	C19H16F3N3O
Molecular Weight	359.35 g/mol
Synonyms	1-(Cyanomethyl)-N-[3-(trifluoromethyl)phenyl]-3,4-dihydroisoquinoline-2(1H)-carboxamide; 1-(Cyanomethyl)-N-[3-(trifluoromethyl)phenyl]-1,2,3,4-tetrahydroisoquinoline-2-carboxamide; 2(1H)-Isoquinolinecarboxamide, 1-(cyanomethyl)-N-[3-(trifluoromethyl)phenyl]-3,4-dihydro-; 339011-95-9; UNII-8V0Q4F3K7U; 8V0Q4F3K7U; CHEMBL3183450; DTXSID60622369
EINECS	Contact for details

Quality Control

Our 1-(Cyanomethyl)-n-[3-(Trifluoromethyl)Phenyl]-3,4-Dihydro-2(1H)-Isoquinolinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.