Description

[1,1'-Biphenyl]-4-Yl[2-(4-Chlorophenyl)-1,3-Thiazol-5-Yl]Methanone CAS NO 339008-20-7 is a high-purity, complex organic compound featuring a biphenyl core linked to a chlorophenyl-substituted thiazole moiety via a ketone bridge. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a key building block in organic synthesis. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

This specialized chemical serves as a critical precursor in several high-value research and manufacturing sectors.

• Pharmaceutical Intermediate: Core building block for the synthesis of potential drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in developing novel pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a potential electron-transport or host material in the fabrication of advanced display technologies due to its conjugated system.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and material science exploration.
• Custom Synthesis: Employed in contract research organizations (CROs) and CDMOs for client-specific molecule construction.

Basic Information

Product Name	[1,1'-Biphenyl]-4-Yl[2-(4-Chlorophenyl)-1,3-Thiazol-5-Yl]Methanone
CAS No.	339008-20-7
Molecular Formula	C22H14ClNOS
Molecular Weight	375.87 g/mol
Synonyms	4-([1,1'-Biphenyl]-4-ylcarbonyl)-2-(4-chlorophenyl)-1,3-thiazole; 2-(4-Chlorophenyl)-5-(4-phenylbenzoyl)thiazole; [1,1'-Biphenyl]-4-yl[2-(4-chlorophenyl)-1,3-thiazol-5-yl]methanone; (4-Biphenylyl)[2-(4-chlorophenyl)-5-thiazolyl]methanone; 339008-20-7; Biphenyl-thiazole ketone derivative
EINECS	Contact for details

Quality Control

Our production of [1,1'-Biphenyl]-4-Yl[2-(4-Chlorophenyl)-1,3-Thiazol-5-Yl]Methanone adheres to stringent quality protocols. Each batch is manufactured under controlled conditions and undergoes comprehensive analytical testing to ensure high purity and batch-to-batch consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality system is designed to meet the exacting standards of GMP-grade intermediate production for advanced research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.