Description

3-[(4-Chlorophenyl)Sulfonyl]-2,5-Dihydro-1H-1Lambda6-Thiophene-1,1-Dione is a high-value, specialized sulfone derivative with a unique cyclic sulfone structure. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in sophisticated organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used as a precursor in the synthesis of new-generation herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Material Science: Serves as a monomer or additive in the development of specialty polymers, high-performance resins, and advanced electronic materials.
• Organic Synthesis Building Block: Utilized in Suzuki-Miyaura, Buchwald-Hartwig, and other cross-coupling reactions to introduce the (4-chlorophenyl)sulfonyl moiety into complex molecular architectures.
• Ligand and Catalyst Development: Acts as a precursor for creating novel ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a tool compound in biochemical assays.

Basic Information

Product Name	3-[(4-Chlorophenyl)Sulfonyl]-2,5-Dihydro-1H-1Lambda6-Thiophene-1,1-Dione
CAS No.	339008-19-4
Molecular Formula	C10H7ClO4S2
Molecular Weight	290.74 g/mol
Synonyms	3-(4-Chlorophenylsulfonyl)-2,5-dihydrothiophene 1,1-dioxide; 3-(p-Chlorophenylsulfonyl)-2,5-dihydrothiophene 1,1-dioxide; 2,5-Dihydro-3-[(4-chlorophenyl)sulfonyl]thiophene 1,1-dioxide; 3-(4-Chlorobenzenesulfonyl)-2,5-dihydrothiophene 1,1-dioxide; 4-Chlorophenyl 2,5-dihydro-1,1-dioxo-1lambda6-thiophen-3-yl sulfone; CAS 339008-19-4
EINECS	Contact for details

Quality Control

Our production of 3-[(4-Chlorophenyl)Sulfonyl]-2,5-Dihydro-1H-1Lambda6-Thiophene-1,1-Dione adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. All material is characterized by advanced analytical techniques including HPLC, GC-MS, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.