Description

1-(2-Anilino-1,3-Thiazol-5-Yl)-2,2-Dimethyl-1-Propanone CAS NO 339008-05-8 is a specialized organic compound featuring a thiazole core substituted with an anilino group and a bulky ketone moiety. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block in synthetic organic chemistry. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Material Science Research: Serves as a precursor for the development of organic semiconductors, liquid crystals, or photoactive materials due to its conjugated system.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic & Institutional Research: Employed in university and institutional labs for methodological studies in heterocyclic chemistry and new reaction development.

Basic Information

Product Name	1-(2-Anilino-1,3-Thiazol-5-Yl)-2,2-Dimethyl-1-Propanone
CAS No.	339008-05-8
Molecular Formula	C₁₄H₁₆N₂OS
Molecular Weight	260.35 g/mol
Synonyms	2,2-Dimethyl-1-(2-phenylamino-1,3-thiazol-5-yl)propan-1-one; 5-Pivaloyl-2-(phenylamino)thiazole; 1-(2-Anilino-1,3-thiazol-5-yl)-2,2-dimethylpropan-1-one; 5-(2,2-Dimethylpropionyl)-2-(phenylamino)thiazole; 2-(Phenylamino)-5-pivaloylthiazole; N-Phenyl-5-pivaloylthiazol-2-amine; CAS 339008-05-8
EINECS	Contact for details

Quality Control

Our production of 1-(2-Anilino-1,3-Thiazol-5-Yl)-2,2-Dimethyl-1-Propanone adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.