Description

Ethyl 4-[(3-Chloro-2-Thienyl)Carbonyl]-3-Isoxazolecarboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure combining isoxazole and thiophene moieties. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, leveraging its heterocyclic core for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and exploring novel chemical spaces.
• Material Science Precursor: Investigated for the synthesis of organic electronic materials and functional polymers due to its conjugated system.

Basic Information

Product Name	Ethyl 4-[(3-Chloro-2-Thienyl)Carbonyl]-3-Isoxazolecarboxylate
CAS No.	338982-48-2
Molecular Formula	C11H8ClNO4S
Molecular Weight	285.70 g/mol
Synonyms	Ethyl 4-(3-chlorothiophene-2-carbonyl)isoxazole-3-carboxylate; 3-Isoxazolecarboxylic acid, 4-[(3-chloro-2-thienyl)carbonyl]-, ethyl ester; 4-[(3-Chloro-2-thienyl)carbonyl]-3-isoxazolecarboxylic acid ethyl ester; Ethyl 4-(3-chloro-2-thiophenecarbonyl)-3-isoxazolecarboxylate; CAS 338982-48-2; 338982-48-2
EINECS	Contact for details

Quality Control

Our Ethyl 4-[(3-Chloro-2-Thienyl)Carbonyl]-3-Isoxazolecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.