Description

3-[(2,2-Dimethylpropanoyl)Amino]-2-Thiophenecarboxylic Acid is a high-purity, specialized organic building block featuring a thiophene core functionalized with a pivalamido and a carboxylic acid group. This compound matters as a critical intermediate in advanced organic synthesis, enabling the construction of complex molecules with precise structural control. Pharmaceutical, agrochemical, and advanced materials researchers need it for developing novel active ingredients, functional polymers, and ligands for catalysis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Advanced Material Monomer: Functional component in the synthesis of conductive polymers, organic semiconductors, and specialty polymers for electronic applications.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial R&D labs.
• Custom Synthesis Starting Material: Supplied to contract research and manufacturing organizations (CROs/CMOs) for the production of bespoke fine chemicals.

Basic Information

Item	Details
Product Name	3-[(2,2-Dimethylpropanoyl)Amino]-2-Thiophenecarboxylic Acid
CAS No.	338982-37-9
Molecular Formula	C11H15NO3S
Molecular Weight	241.31 g/mol
Synonyms	3-Pivalamido-2-thiophenecarboxylic acid; 2-Thiophenecarboxylic acid, 3-[(2,2-dimethyl-1-oxopropyl)amino]-; 3-(Pivaloylamino)thiophene-2-carboxylic acid; 3-[(2,2-Dimethylpropanoyl)amino]thiophene-2-carboxylic acid; Pivalic acid (3-carboxy-2-thienyl)amide; 3-Amino-2-thiophenecarboxylic acid pivalamide derivative
EINECS	Contact for details

Quality Control

Every batch of 3-[(2,2-Dimethylpropanoyl)Amino]-2-Thiophenecarboxylic Acid is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure reliable purity and batch-to-batch consistency for your critical R&D and scale-up processes. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles by HPLC, NMR, and MS are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.