Description

5-(Bromomethyl)-1-Methyl-3-(Trifluoromethyl)-1H-Thieno[2,3-C]Pyrazole CAS NO 338982-24-4 is a high-value, multi-functional heterocyclic building block designed for advanced organic synthesis. Its core value lies in the strategic combination of a reactive bromomethyl handle and a stable, electron-deficient trifluoromethylated thienopyrazole scaffold, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries seeking to incorporate novel, potent pharmacophores into their target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics targeting challenging disease pathways.
• Agrochemical Research: Serves as a versatile scaffold for developing new generations of herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Used in the research and development of advanced organic electronic materials, such as organic semiconductors and light-emitting diodes (OLEDs), due to its electron-accepting properties.
• Chemical Biology & Probe Development: Employed as a building block for creating fluorescent probes, affinity labels, and other tool compounds for studying biological systems and drug-target interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a functionalized thienopyrazole moiety.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries for high-throughput screening in early-stage drug discovery campaigns.

Basic Information

Product Name	5-(Bromomethyl)-1-Methyl-3-(Trifluoromethyl)-1H-Thieno[2,3-C]Pyrazole
CAS No.	338982-24-4
Molecular Formula	C9H6BrF3N2S
Molecular Weight	311.12 g/mol
Synonyms	1-Methyl-3-(trifluoromethyl)-5-(bromomethyl)-1H-thieno[2,3-c]pyrazole; 5-(Bromomethyl)-1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole; 1H-Thieno[2,3-c]pyrazole, 5-(bromomethyl)-1-methyl-3-(trifluoromethyl)-; Thieno[2,3-c]pyrazole bromomethyl derivative; 338982-24-4; 5-Bromomethyl-1-methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole
EINECS	Contact for details

Quality Control

Our production of 5-(Bromomethyl)-1-Methyl-3-(Trifluoromethyl)-1H-Thieno[2,3-C]Pyrazole adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and GC-MS for solvent residue analysis, to ensure consistency and reliability. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support cGMP compliance for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.