Description

1-Methyl-3-(Trifluoromethyl)-1H-Thieno[2,3-C]Pyrazole-5-Carboxylic Acid is a high-value, multifunctional heterocyclic building block prized for its unique molecular architecture. Its core value lies in serving as a critical intermediate for the synthesis of advanced pharmaceutical compounds and agrochemicals, enabling the introduction of the metabolically stable trifluoromethyl group and the versatile carboxylic acid moiety. This compound is essential for research and development chemists in the life sciences sector, particularly those focused on creating novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in areas like kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the thienopyrazole scaffold contributes to biological activity.
• Material Science Research: Acts as a precursor for functionalized organic molecules used in organic electronics, such as OLED materials or conductive polymers.
• Chemical Biology & Proteomics: Employed as a building block for activity-based probes (ABPs) or photoaffinity labels to study enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring complex heterocyclic cores.

Basic Information

Product Name	1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylic acid
CAS No.	338982-15-3
Molecular Formula	C8H5F3N2O2S
Molecular Weight	250.20 g/mol
Synonyms	1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylic acid; 1-Methyl-3-trifluoromethyl-1H-thieno[2,3-c]pyrazole-5-carboxylic acid; Thieno[2,3-c]pyrazole-5-carboxylic acid, 1-methyl-3-(trifluoromethyl)-1H-; 338982-15-3; 1H-Thieno[2,3-c]pyrazole-5-carboxylic acid, 1-methyl-3-(trifluoromethyl)-; CAS 338982-15-3
EINECS	Contact for details

Quality Control

Our production of 1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazole-5-carboxylic acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical and agrochemical R&D. Certificates of Analysis (COA) with full traceability are provided for each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its carboxylic acid nature, keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.