Description

[5-(Dimethylamino)-4-Phenyl-2-Thienyl](4-Fluorophenyl)Methanone is a specialized organic compound featuring a thiophene core substituted with dimethylamino and phenyl groups, and a 4-fluorobenzoyl moiety. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate (API intermediate) and a versatile building block in synthetic organic chemistry. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Research: Serves as a building block for developing new active ingredients for crop protection products, leveraging its heterocyclic and fluorinated structure.
• Organic Synthesis Building Block: Used in cross-coupling reactions, carbonyl chemistry, and heterocyclic functionalization to create complex molecular libraries for screening.
• Material Science Research: Potential monomer or dopant in the development of organic semiconductors, conductive polymers, or advanced organic materials due to its electron-donating and accepting groups.
• Chemical Reference Standard: Utilized as a high-purity standard in analytical laboratories for method development, validation, and quality control of related substances.

Basic Information

Product Name	[5-(Dimethylamino)-4-Phenyl-2-Thienyl](4-Fluorophenyl)Methanone
CAS No.	338976-04-8
Molecular Formula	C19H16FNO1S
Molecular Weight	325.40 g/mol
Synonyms	(4-Fluorophenyl)[5-(dimethylamino)-4-phenyl-2-thienyl]methanone; 5-(Dimethylamino)-4-phenyl-2-thienyl(4-fluorophenyl)methanone; Methanone, [5-(dimethylamino)-4-phenyl-2-thienyl](4-fluorophenyl)-; 4-Fluoro-[5-(dimethylamino)-4-phenyl-thiophen-2-yl]-phenylmethanone; 2-Thiophenemethanone, 5-(dimethylamino)-4-phenyl-, 4-fluorophenyl derivative
EINECS	Contact for details

Quality Control

Our production of [5-(Dimethylamino)-4-Phenyl-2-Thienyl](4-Fluorophenyl)Methanone adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We operate under a cGMP-compliant quality management system, and specifications can be aligned with client-specific pharmacopeial or internal standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.