Description

2-([4-(Trifluoromethyl)Anilino]Methylene)Dihydropyrrolo[2,1-B][1,3]Thiazole-3,5(2H,6H)-Dione is a high-value, specialized heterocyclic compound featuring a fused pyrrolothiazole-dione core with a trifluoromethyl-substituted anilino methylene moiety. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate and a versatile building block in modern organic synthesis. It is primarily utilized by research institutions and industrial manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials. The compound's structure is designed to impart specific biological activity and physicochemical properties to final products.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in therapeutic areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used as a building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole and pyrrolidine rings.
• Organic Synthesis & Material Science: Acts as a versatile scaffold for constructing complex heterocyclic systems for applications in organic electronics, ligands for catalysis, and specialty polymers.
• Biochemical Tool Compound: Employed in life science research as a probe or inhibitor to study specific enzymatic pathways and biological mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	2-([4-(Trifluoromethyl)Anilino]Methylene)Dihydropyrrolo[2,1-B][1,3]Thiazole-3,5(2H,6H)-Dione
CAS No.	338960-08-0
Molecular Formula	C15H10F3N3O2S
Molecular Weight	353.32 g/mol
Synonyms	2-[(4-Trifluoromethylphenylamino)methylene]dihydropyrrolo[2,1-b][1,3]thiazole-3,5-dione; 2-((4-(Trifluoromethyl)phenylimino)methyl)-3a,4,6,6a-tetrahydro-3H-pyrrolo[2,1-b][1,3]thiazole-3,5-dione; Pyrrolo[2,1-b]thiazole-3,5-dione, 2-[[[4-(trifluoromethyl)phenyl]amino]methylene]hexahydro-; CAS 338960-08-0; (Z)-2-((4-(Trifluoromethyl)phenylimino)methyl)-3a,4,6,6a-tetrahydro-1H-pyrrolo[2,1-b][1,3]thiazole-3,5(2H,6H)-dione
EINECS	Contact for details

Quality Control

Every batch of 2-([4-(Trifluoromethyl)Anilino]Methylene)Dihydropyrrolo[2,1-B][1,3]Thiazole-3,5(2H,6H)-Dione is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support compliance with global regulatory frameworks, including REACH.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from degradation. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.