Description

2-(Acetylamino)-5-Chloro-3-Thiophenecarboxylic Acid is a high-purity, functionalized thiophene derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce specific chlorinated thiophene motifs into their target structures.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel drug candidates, particularly in therapeutic areas requiring heterocyclic cores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that leverage the thiophene moiety for biological activity.
• Material Science Research: Serves as a monomer or functional unit in the synthesis of conductive polymers, organic semiconductors, and other specialty materials.
• Chemical Research & Development: Employed as a versatile building block for exploring new chemical reactions and creating libraries of compounds for high-throughput screening.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Item	Detail
Product Name	2-(Acetylamino)-5-Chloro-3-Thiophenecarboxylic Acid
CAS No.	338777-32-5
Molecular Formula	C7H6ClNO3S
Molecular Weight	219.64 g/mol
Synonyms	5-Chloro-2-acetamidothiophene-3-carboxylic Acid; 2-Acetamido-5-chlorothiophene-3-carboxylic Acid; N-(5-Chloro-3-carboxythiophen-2-yl)acetamide; 2-Acetylamino-5-chloro-3-thiophenecarboxylic Acid; 5-Chloro-2-(acetylamino)thiophene-3-carboxylic Acid; Acetamide, N-(5-chloro-3-carboxy-2-thienyl)-; 338777-32-5
EINECS	Contact for details

Quality Control

Every batch of 2-(Acetylamino)-5-Chloro-3-Thiophenecarboxylic Acid is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the precise requirements of your synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.