Description

Ethyl 1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-3-Phenyl-1H-Indole-2-Carboxylate is a high-value, multi-functional heterocyclic compound that serves as a critical synthetic intermediate in advanced chemical research and development. Its complex molecular architecture, featuring indole, pyridine, and trifluoromethyl groups, makes it an essential building block for creating novel molecules with targeted properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in developing new generations of pesticides and herbicides, where the trifluoromethyl and chloro-pyridine motifs can enhance biological activity and environmental stability.
• Material Science: Serves as a monomer or functional additive in the research of advanced polymers and organic electronic materials due to its conjugated indole system.
• Chemical Biology: Employed as a molecular probe or scaffold in biochemical research to study protein-ligand interactions and enzyme inhibition.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to global R&D clients.

Basic Information

Product Name	Ethyl 1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-3-Phenyl-1H-Indole-2-Carboxylate
CAS No.	338748-77-9
Molecular Formula	C23H16ClF3N2O2
Molecular Weight	444.83 g/mol
Synonyms	Ethyl 1-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-3-phenyl-1H-indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 1-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-3-phenyl-, ethyl ester; CAS 338748-77-9; 338748-77-9; Ethyl 3-phenyl-1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]indole-2-carboxylate; 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-phenyl-1H-indole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 1-[3-Chloro-5-(Trifluoromethyl)-2-Pyridinyl]-3-Phenyl-1H-Indole-2-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized using advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the product under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.