Description

4-Methyl-5-[1-Methyl-3-(Trifluoromethyl)-1H-Thieno[2,3-C]Pyrazol-5-Yl]-4H-1,2,4-Triazole-3-Thiol is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure incorporating thiophene, pyrazole, and triazole moieties. This compound is critical for the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers for synthesizing new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science: Serves as a precursor for specialty polymers and advanced organic electronic materials due to its conjugated system.
• Chemical Biology: Employed as a molecular probe or scaffold in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	4-Methyl-5-[1-Methyl-3-(Trifluoromethyl)-1H-Thieno[2,3-C]Pyrazol-5-Yl]-4H-1,2,4-Triazole-3-Thiol
CAS No.	338747-58-3
Molecular Formula	C₁₁H₈F₃N₅S₂
Molecular Weight	331.34 g/mol
Synonyms	4-Methyl-5-(1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl)-4H-1,2,4-triazole-3-thiol; 4H-1,2,4-Triazole-3-thiol, 4-methyl-5-[1-methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl]-; CAS 338747-58-3; Thieno[2,3-c]pyrazole-triazole thiol derivative; 1-Methyl-3-(trifluoromethyl)-1H-thieno[2,3-c]pyrazol-5-yl triazolethiol
EINECS	Contact for details

Quality Control

Our 4-Methyl-5-[1-Methyl-3-(Trifluoromethyl)-1H-Thieno[2,3-C]Pyrazol-5-Yl]-4H-1,2,4-Triazole-3-Thiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with client specifications and relevant ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.