Description

2-Oxabicyclo[4.1.0]Heptane-5,7-Dicarboxylicacid,5-Amino-,(1R,5R,6S,7R)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic amino acid derivative. This compound serves as a critical chiral building block and advanced intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research. It is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), where its rigid, functionalized structure enables the construction of specific three-dimensional architectures.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Asymmetric Synthesis: Used as a precursor or ligand in catalytic asymmetric reactions to induce high enantioselectivity.
• Peptidomimetics & Conformationally Restricted Analogues: Incorporated into peptide backbones to enhance metabolic stability, bioavailability, and receptor selectivity.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds to study enzyme mechanisms and protein-protein interactions.
• Agrochemical Research: Potential intermediate in the synthesis of novel, biologically active compounds for crop protection.
• Academic & Industrial R&D: A valuable reagent for methodology development and exploring new chemical space in organic chemistry.

Basic Information

Product Name	2-Oxabicyclo[4.1.0]Heptane-5,7-Dicarboxylicacid,5-Amino-,(1R,5R,6S,7R)-Rel-(9Ci)
CAS No.	338468-41-0
Molecular Formula	C9H11NO6
Molecular Weight	229.19 g/mol
Synonyms	(1R,5R,6S,7R)-5-Amino-2-oxabicyclo[4.1.0]heptane-5,7-dicarboxylic acid; rel-(1R,5R,6S,7R)-5-Amino-2-oxabicyclo[4.1.0]heptane-5,7-dicarboxylic acid; 5-Amino-2-oxabicyclo[4.1.0]heptane-5,7-dicarboxylic acid, (1R,5R,6S,7R)-rel-; Bicyclic amino acid derivative CAS 338468-41-0; 2-Oxabicyclo[4.1.0]heptane-5,7-dicarboxylic acid, 5-amino-, (1R,5R,6S,7R)-rel-
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management protocols. We employ advanced analytical techniques, including chiral HPLC and NMR, to ensure excellent chemical and enantiomeric purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under dry, inert conditions to maintain stability. For long-term storage, consider storage under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.