Description

1H-Indazole-5-Boronic Acid CAS NO 338454-14-1 is a high-purity boronic acid derivative, a key building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used to create new active ingredients for crop protection products through structure-activity relationship (SAR) studies.
• Material Science: Serves as a building block for organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology: Employed in the development of molecular probes and bioconjugation reagents for target identification and validation.
• Catalyst Ligand Synthesis: Used to construct sophisticated ligand frameworks for transition metal catalysis.
• Academic & Contract Research: A fundamental reagent for method development and discovery chemistry in academic and CRO laboratories.

Basic Information

Product Name	1H-Indazole-5-Boronic Acid
CAS No.	338454-14-1
Molecular Formula	C7H7BN2O2
Molecular Weight	161.96 g/mol
Synonyms	5-Indazoleboronic Acid; 1H-Indazol-5-ylboronic Acid; (1H-Indazol-5-yl)boronic Acid; Indazole-5-boronic Acid; B-(1H-Indazol-5-yl)boronic Acid; 338454-14-1; 5-Boron-1H-indazole
EINECS	Contact for details

Quality Control

Our 1H-Indazole-5-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards required for cGMP and ISO-certified production environments, ensuring reliability for your most critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic nature, store under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.