Description

2-(2-Pyridinyl)-6-(Trifluoromethyl)-4-Pyrimidinethiol is a high-value heterocyclic building block featuring a pyridine ring, a trifluoromethyl group, and a thiol functionality. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its unique structure imparts desirable biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides leveraging the trifluoromethyl group's properties.
• Ligand Precursor: Serves as a precursor for metal-chelating ligands in catalysis and material science applications.
• Organic Electronics Research: Investigated as a component for electron-transport materials or as a functional group in molecular engineering.
• Chemical Biology Probes: Utilized in the development of biochemical probes and tool compounds for studying enzyme function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke molecules for client projects.

Basic Information

Product Name	2-(2-Pyridinyl)-6-(Trifluoromethyl)-4-Pyrimidinethiol
CAS No.	338418-16-9
Molecular Formula	C10H6F3N3S
Molecular Weight	257.24 g/mol
Synonyms	6-(Trifluoromethyl)-2-(2-pyridinyl)-4-pyrimidinethiol; 2-(Pyridin-2-yl)-6-(trifluoromethyl)pyrimidine-4-thiol; 4-Pyrimidinethiol, 2-(2-pyridinyl)-6-(trifluoromethyl)-; 2-(2-Pyridyl)-6-trifluoromethyl-4-pyrimidinethiol; 6-Trifluoromethyl-2-(2-pyridyl)pyrimidine-4-thiol; 2-Pyridin-2-yl-6-trifluoromethyl-pyrimidine-4-thiol
EINECS	Contact for details

Quality Control

Our 2-(2-Pyridinyl)-6-(Trifluoromethyl)-4-Pyrimidinethiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to oxidize, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container has been opened.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.