Description

1-[2-(4-Chlorophenyl)-1,3-Thiazol-5-Yl]-3-(Dimethylamino)-2-Propen-1-One is a high-purity, advanced pharmaceutical intermediate and research chemical of significant commercial interest. This compound is valued for its role as a key building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry and agrochemical research. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for developing new therapeutic and crop protection agents.

Application

• Key intermediate in the synthesis of novel pharmaceutical candidates, particularly for kinase inhibitors and anti-inflammatory agents.
• Building block for advanced agrochemical research, including the development of new fungicides and herbicides.
• Precursor in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Research chemical in academic and industrial laboratories exploring heterocyclic chemistry and organic synthesis.
• Starting material for the production of specialized dyes and functional materials requiring specific chromophores.
• Component in the development of chemical probes and biochemical tools for biological target identification.

Basic Information

Product Name	1-[2-(4-Chlorophenyl)-1,3-Thiazol-5-Yl]-3-(Dimethylamino)-2-Propen-1-One
CAS No.	338414-64-5
Molecular Formula	C14H13ClN2OS
Molecular Weight	292.78 g/mol
Synonyms	1-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-3-(dimethylamino)-2-propen-1-one; (E)-1-[2-(4-Chlorophenyl)-1,3-thiazol-5-yl]-3-(dimethylamino)prop-2-en-1-one; 3-(Dimethylamino)-1-[2-(4-chlorophenyl)-1,3-thiazol-5-yl]prop-2-en-1-one; 338414-64-5; 1-(2-(4-Chlorophenyl)thiazol-5-yl)-3-(dimethylamino)prop-2-en-1-one; Enaminone derivative; Chlorophenyl thiazole enaminone
EINECS	Contact for details

Quality Control

Our production of 1-[2-(4-Chlorophenyl)-1,3-Thiazol-5-Yl]-3-(Dimethylamino)-2-Propen-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is characterized and released against comprehensive specifications, including identity confirmation by spectroscopic methods and purity determination by HPLC. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.