Description

5-(2-Phenyl-1,3-thiazol-5-yl)isoxazole is a high-purity heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique fused-ring structure, combining isoxazole and thiazole moieties, makes it a valuable intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research and development teams in the pharmaceutical, agrochemical, and material science industries for lead optimization and the creation of new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold for bioactivity.
• Material Science Precursor: Serves as a building block for organic semiconductors, liquid crystals, and photoactive materials due to its conjugated system.
• Chemical Biology Probe: Employed in medicinal chemistry to study protein-ligand interactions and enzyme inhibition mechanisms.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploration of new heterocyclic chemistry.

Basic Information

Product Name	5-(2-Phenyl-1,3-thiazol-5-yl)isoxazole
CAS No.	338414-59-8
Molecular Formula	C12H8N2OS
Molecular Weight	228.27 g/mol
Synonyms	5-(2-Phenyl-1,3-thiazol-5-yl)-1,2-oxazole; 5-(2-Phenylthiazol-5-yl)isoxazole; 338414-59-8; Isoxazole, 5-(2-phenyl-5-thiazolyl)-; 2-Phenyl-5-(isoxazol-5-yl)thiazole; 5-(2-Phenyl-1,3-thiazolyl)isoxazole
EINECS	Contact for details

Quality Control

Every batch of 5-(2-Phenyl-1,3-thiazol-5-yl)isoxazole is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.