Description

1-(2-Phenyl-1,3-thiazol-5-yl)-3-[3-(trifluoromethyl)anilino]-2-propen-1-one is a high-purity, advanced pharmaceutical intermediate characterized by its distinct thiazole and chalcone-based molecular architecture. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for developing potential therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Biochemical Tool Compound: Serves as a research probe for studying enzyme inhibition and receptor interactions in biological systems.
• Organic Synthesis: Utilized in complex organic transformations to create libraries of heterocyclic compounds for screening.
• Agrochemical Development: Investigated as a precursor for developing new active ingredients with potential pesticidal or herbicidal activity.

Basic Information

Product Name	1-(2-Phenyl-1,3-thiazol-5-yl)-3-[3-(trifluoromethyl)anilino]-2-propen-1-one
CAS No.	338414-56-5
Molecular Formula	C19H13F3N2OS
Molecular Weight	374.38 g/mol
Synonyms	(E)-1-(2-Phenyl-1,3-thiazol-5-yl)-3-((3-(trifluoromethyl)phenyl)amino)prop-2-en-1-one; 3-[(E)-3-(2-Phenyl-1,3-thiazol-5-yl)-3-oxoprop-1-en-1-yl]-1-(trifluoromethyl)aniline; 1-(2-Phenyl-1,3-thiazol-5-yl)-3-[3-(trifluoromethyl)anilino]-2-propen-1-one; 5-[(1E)-3-[[3-(Trifluoromethyl)phenyl]amino]-3-oxo-1-propen-1-yl]-2-phenyl-1,3-thiazole; Chalcone derivative bearing thiazole and trifluoromethyl aniline moieties.
EINECS	Contact for details

Quality Control

Our 1-(2-Phenyl-1,3-thiazol-5-yl)-3-[3-(trifluoromethyl)anilino]-2-propen-1-one is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.