Description

2-Fluoro-n-[1-(5-Methyl-1H-1,3-Benzimidazol-2-Yl)Ethyl]Benzenecarboxamide is a high-purity, advanced pharmaceutical intermediate featuring a benzimidazole core with a fluorinated aromatic substituent. This compound is of significant value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially those targeting specific enzyme or receptor pathways.
• Protease Inhibitor Research: The benzimidazole moiety is a common pharmacophore in the development of protease inhibitors for virology and oncology applications.
• Kinase Inhibitor Development: Serves as a core structure in the design and optimization of kinase inhibitors for cancer and inflammatory disease treatments.
• Chemical Biology Probes: Used in academic and industrial research to create molecular probes for studying biological processes and target validation.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Preclinical & Process Chemistry: Employed during preclinical development and process chemistry scale-up for new chemical entities (NCEs).

Basic Information

Product Name	2-Fluoro-n-[1-(5-Methyl-1H-1,3-Benzimidazol-2-Yl)Ethyl]Benzenecarboxamide
CAS No.	338410-65-4
Molecular Formula	C17H16FN3O
Molecular Weight	297.33 g/mol
Synonyms	2-Fluoro-N-[1-(5-methyl-1H-benzimidazol-2-yl)ethyl]benzamide; Benzenecarboxamide, 2-fluoro-N-[1-(5-methyl-1H-benzimidazol-2-yl)ethyl]-; N-(1-(5-Methyl-1H-benzo[d]imidazol-2-yl)ethyl)-2-fluorobenzamide; 2-Fluoro-N-(1-(5-methyl-1H-benzoimidazol-2-yl)ethyl)benzamide
EINECS	Contact for details

Quality Control

Our production of 2-Fluoro-n-[1-(5-Methyl-1H-1,3-Benzimidazol-2-Yl)Ethyl]Benzenecarboxamide adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.