Description

Dimethyl 5-Amino-3-(2-Methoxy-2-Oxoethyl)-2,4-Thiophenedicarboxylate is a high-purity, multifunctional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring protected amino and ester functionalities on a thiophene core, makes it a versatile precursor for constructing complex pharmacophores and functional materials. This compound is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a crucial building block for creating advanced herbicides, fungicides, and insecticides with novel modes of action.
• Material Science Precursor: Used in the synthesis of functionalized thiophene-based polymers and small molecules for applications in organic electronics, such as OLEDs and organic photovoltaics.
• Dye and Pigment Chemistry: Acts as an intermediate for producing specialized heterocyclic dyes and pigments with specific light-absorption properties.
• Ligand and Catalyst Development: Provides a scaffold for creating novel chelating ligands and organocatalysts used in asymmetric synthesis.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthesis projects and scale-up development.

Basic Information

Product Name	Dimethyl 5-Amino-3-(2-Methoxy-2-Oxoethyl)-2,4-Thiophenedicarboxylate
CAS No.	338393-14-9
Molecular Formula	C11H13NO6S
Molecular Weight	287.29 g/mol
Synonyms	5-Amino-3-(2-methoxy-2-oxoethyl)thiophene-2,4-dicarboxylic acid dimethyl ester; Dimethyl 5-amino-3-(carboxymethyl)thiophene-2,4-dicarboxylate, methyl ester; 2,4-Thiophenedicarboxylic acid, 5-amino-3-(2-methoxy-2-oxoethyl)-, dimethyl ester; Methyl 2-(5-amino-3,4-bis(methoxycarbonyl)thiophen-2-yl)acetate; 338393-14-9; Thiophene building block CAS 338393-14-9
EINECS	Contact for details

Quality Control

Our Dimethyl 5-Amino-3-(2-Methoxy-2-Oxoethyl)-2,4-Thiophenedicarboxylate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material is suitable for demanding R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.