Description

5-Chloro-1-(4-Nitrobenzyl)-3-Phenyl-2-(Trifluoromethyl)-1H-Indole is a high-purity, multi-functional indole derivative of significant interest in advanced organic synthesis. This compound serves as a critical specialized building block for the development of novel chemical entities, particularly in the pharmaceutical and agrochemical sectors. Its unique molecular architecture, featuring chloro, nitro, phenyl, and trifluoromethyl substituents, makes it an essential intermediate for researchers and process chemists focused on creating complex heterocyclic frameworks with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for anti-inflammatory, anticancer, and central nervous system (CNS) targeted therapies.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, leveraging the biological activity of the indole core and its substituents.
• Material Science: Serves as a building block for advanced organic materials, including organic light-emitting diodes (OLEDs) and specialty polymers.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tag in the study of biological pathways and protein interactions.
• Academic & Contract Research: Essential for fundamental research in synthetic organic chemistry and medicinal chemistry at universities and CROs (Contract Research Organizations).
• Fine Chemical Synthesis: Used in custom synthesis and scale-up projects for producing complex, high-value specialty chemicals.

Basic Information

Product Name	5-Chloro-1-(4-Nitrobenzyl)-3-Phenyl-2-(Trifluoromethyl)-1H-Indole
CAS No.	337921-12-7
Molecular Formula	C22H14ClF3N2O2
Molecular Weight	430.81 g/mol
Synonyms	5-Chloro-1-[(4-nitrophenyl)methyl]-3-phenyl-2-(trifluoromethyl)-1H-indole; 1-(4-Nitrobenzyl)-5-chloro-3-phenyl-2-(trifluoromethyl)indole; 5-Chloro-1-(4-nitrobenzyl)-3-phenyl-2-(trifluoromethyl)indole; 337921-12-7; 5-Chloro-1-(4-nitrobenzyl)-3-phenyl-2-trifluoromethylindole; 2-(Trifluoromethyl)-5-chloro-1-(4-nitrobenzyl)-3-phenyl-1H-indole
EINECS	Contact for details

Quality Control

Our 5-Chloro-1-(4-Nitrobenzyl)-3-Phenyl-2-(Trifluoromethyl)-1H-Indole is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as identity, assay, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and development, as well as scale-up activities in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.