Description

1-(1-Boc-Piperidin-4-Yl)-5-Nitro-1,3-Dihydro-1H-Benzoimidazol-2-One is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, enabling the creation of novel therapeutic agents with enhanced biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers focused on developing innovative treatments in areas such as oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Drug Discovery Scaffold: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Protease Inhibitor Synthesis: Serves as a core structural component in the development of protease inhibitors for various therapeutic targets.
• Kinase Inhibitor Development: Employed in the construction of kinase inhibitor candidates for oncology and inflammatory disease research.
• Chemical Biology Probes: Utilized to create tool compounds for investigating specific biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	1-(1-Boc-Piperidin-4-Yl)-5-Nitro-1,3-Dihydro-1H-Benzoimidazol-2-One
CAS No.	337910-14-2
Molecular Formula	C17H22N4O5
Molecular Weight	362.38 g/mol
Synonyms	1-(1-Boc-4-Piperidinyl)-5-Nitro-1,3-Dihydro-2H-Benzimidazol-2-One; 5-Nitro-1-(1-tert-butoxycarbonyl-4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one; 1-(1-(tert-Butoxycarbonyl)piperidin-4-yl)-5-nitro-1,3-dihydro-2H-benzimidazol-2-one; 1-(1-Boc-piperidin-4-yl)-5-nitro-1,3-dihydro-2H-benzimidazol-2-one; 337910-14-2; tert-Butyl 4-(5-nitro-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 1-(1-Boc-Piperidin-4-Yl)-5-Nitro-1,3-Dihydro-1H-Benzoimidazol-2-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.