Description

1-(2-tert-Butoxy-2-Oxoethyl)-1H-Indole-5-Carboxylic Acid is a high-purity, synthetically valuable indole derivative used as a key building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise molecular scaffolds for developing novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily targeted at the pharmaceutical, agrochemical, and specialty chemical industries for applications in medicinal chemistry and material science research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of complex drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators that leverage the indole core structure.
• Material Science: Acts as a monomer or functional additive in the creation of advanced polymers and organic electronic materials.
• Medicinal Chemistry: Provides a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Bioconjugation: The carboxylic acid group enables its use as a linker molecule for attaching functional groups to biomolecules or surfaces.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists exploring new reactions and methodologies involving indole chemistry.

Basic Information

Product Name	1-(2-tert-Butoxy-2-Oxoethyl)-1H-Indole-5-Carboxylic Acid
CAS No.	336191-97-0
Molecular Formula	C15H17NO4
Molecular Weight	275.30 g/mol
Synonyms	5-Carboxy-1-(2-tert-butoxy-2-oxoethyl)indole; 1H-Indole-5-carboxylic acid, 1-(2-tert-butoxy-2-oxoethyl)-; 1-(tert-Butoxycarbonylmethyl)-1H-indole-5-carboxylic acid; 1-(2-tert-Butoxy-2-oxoethyl)-1H-indole-5-carboxylic acid; 1-(tert-Butoxyoxaloethyl)-5-carboxyindole; 5-Carboxyindole-1-acetic acid tert-butyl ester; tert-Butyl 2-(5-carboxy-1H-indol-1-yl)acetate
EINECS	Contact for details

Quality Control

Our 1-(2-tert-Butoxy-2-Oxoethyl)-1H-Indole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.