Description

6,7-Diethoxy-1-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride, 98 is a high-purity, organic salt derivative of the tetrahydroisoquinoline scaffold, a privileged structure in medicinal chemistry. This compound is a critical pharmaceutical intermediate and a versatile building block for research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules, particularly those targeting neurological and cardiovascular pathways.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and cardiovascular drugs.
• Medicinal Chemistry Research: Serves as a core scaffold for designing and synthesizing new chemical entities (NCEs) for biological screening and structure-activity relationship (SAR) studies.
• Alkaloid Synthesis: Used in the semi-synthesis or total synthesis of complex natural products and alkaloids based on the isoquinoline structure.
• Chemical Reference Standard: High-purity grade suitable for use as an analytical standard in quality control (QC) and research laboratories.
• Academic & Industrial R&D: Fundamental building block for exploratory chemistry in academic institutions and corporate R&D departments focused on drug discovery.
• Process Chemistry Development: Employed in scaling up synthetic routes and optimizing manufacturing processes for target molecules.

Basic Information

Product Name	6,7-Diethoxy-1-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride, 98
CAS No.	336185-27-4
Molecular Formula	C₁₄H₂₁NO₂·HCl
Molecular Weight	271.78 g/mol (Free base: 235.32 g/mol)
Synonyms	1-Methyl-6,7-diethoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 6,7-Diethoxy-1-methyl-3,4-dihydroisoquinoline hydrochloride; 1-Methyl-6,7-diethoxy-3,4-dihydroisoquinoline HCl; 6,7-Diethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline HCl; 1,2,3,4-Tetrahydro-6,7-diethoxy-1-methylisoquinoline hydrochloride; 6,7-Diethoxy-1-methyl-THIQ hydrochloride
EINECS	Contact for details

Quality Control

Our 6,7-Diethoxy-1-Methyl-1,2,3,4-Tetrahydroisoquinoline Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.